Chemical constituents from Liparis nervosa / 中草药

ABSTRACT

Objective: To study the chemical constituents from Liparis nervosa. Methods: The column chromatography on silica gel, MCI gel, ODS, and Sephadex LH-20 columns was applied for the isolation and purification of the chemical constituents. The structures were identified based on physicochemical property and spectral data. Results: Nine compounds were isolated and identified as (hexahydro-1H-pyrrolizin-1-yl) methyl-2, 2-dimethyl-8-(3-hydroxyisoamyl) chroman-6-carboxylate (1), friedelin (2), α-spinasterol (3), p-hydroxybenzaldehyde (4), swertisin (5), 6, 8-di-C-α-L-arabinopyranosyl apigenin (6), 6, 8-di-C-α-L-arabinopyranosyl genkwanin (7), 8-C-α-L-arabinopyranosyl apigenin (8), and thymidine (9). Conclusion: Compound 1 is a new compound named nervosine B, and compounds 2-9 are isolated from L. nervosa for the first time.