Chemical constituents of Humulus scandens / 中草药

ABSTRACT

Objective: To study the chemical constituents of Humulus scandens. Methods: The compounds were isolated and repeatedly purified by silica gel, TLC, and Sephadex LH-20 column chromatography, and their structures were elucidated on the basis of physicochemical constants and spectral analysis. Results: Eleven compounds were obtained and elucidated as (24R)-stigmast-7, 22(E)-dien-3β- ol (1), daucesterol (2), stigmast-3, 6-dione (3), epidioxyergosta-6, 22-dine-3β-ol (4), stigmasterol (5), soya-erebroside II (6), oleanolic acid (7), bis-(2-ethylhexyl) phthalate (8), scopoletin (9), betulimicaciol (10), and soya-erebroside I (11). Conclusion: The compounds 1, 3, 4 and 6-11 are isolated from the plants of Humulus Linn. for the first time.