Chemical constituents from fruits of Dimocarpus longan / 中草药

ABSTRACT

Objective: To investigate the chemical constituents of the fruits of Dimocarpus longan. Methods: The chemical constituents were isolated from 95% alcohol-extract on seeds of longan by silica gel, polyamide, as well as Sephadex LH-20 column chromatography. Their structures were identified on the basis of physical and chemical properties and spectral analysis. Results: Twelve compounds were isolated and identified as β-sitosterol (1), 2-phenylethanol (2), 2-methyl-1,10-undecanediol (3) (24R)-6β-hydroxy-24- ethyl-cholest-4-en-3-one (4), oleanolic acid (5), pinoresinol (6), nicotinic acid (7), 4-hydroxybenzoic acid (8), β-daucosterol (9), 1-O-methyl-D-myo-inositol (10), uracil (11), and adenosine (12). Conclusion: Compounds 2-8 and 10 are reported from the pericarp of longan (the fruits of D. longan) for the first time, and compound 3 is a new compound named longandiol.