Muscarinic M5 receptor subtype and its biologic characterizations / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 10-13, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-857385
ABSTRACT
The fifth muscarinic receptor (M5), the last one of the muscarinic receptor family to be cloned, has the same basic formation characterization as G-protein coupled receptor family. M5 transduces signals by coupling with G-proteins, which then modulate the activities of a number of effector enzymes and ion channels. As M5 also plays a variety of prominent physiological roles by regulating central transmitters NO and DA, it has been considered as a novel drug therapy target for drug addiction, dysfunction of dopamine-ergic nervous system, Alzheimers disease and cerebral ischemia.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2005
Tipo de documento:
Artigo
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