Analysis of Crystalline Substances in a TCM Hospital Preparation for Treatment of Rheumatism / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 549-556, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-857745
ABSTRACT
OBJECTIVE:
To analyze the potential adulterations in a traditional Chinese medicine hospital preparation for the treatment of rheumatism.METHODS:
The suspicious crystalline substances were isolated under a stereoscopic microscope, and analyzed with GC-MS and UHPLC-MS. GC-MS measurements were preformed on an Agilent HP-5MS column with ion electron impact ionization. UHPLC-MS measurements were preformed with Agilent Zorbax SB-C18 as stationary phase and the mixture of acetontrile-0.1% formic acid as mobile phase under electronic spray ionization mode.RESULTS:
Five kinds of chemical drugs were identified from the hospital preparation, including piroxicam, prednisone acetate, indomethacin, ibuprofen and vitamin B2.CONCLUSION:
More attention should be paid to the adulteration in some hospital preparations.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2020
Tipo de documento:
Artigo
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