Review of Excipients Safety in Pediatric Patients / 中国药学杂志

ABSTRACT

Excipients are essential components of pharmaceutical products for use in adults and children. They are generally considered to be inert ingredients and are therefore rarely concerned due to the growth and development of the body of children and the specificity of the pharmacokinetics of pharmaceutical excipients, it is undeniable that children are facing risks of excipient toxicity. This article summarizes some excipients of defined and potential hazardous risks in the pediatric population, and reviews the current status of pediatric use of excipients in China and other countries, therefore to discuss the safety of excipients in children, and to provide a reference to healthcare professionals including pharmacists, physicians, as well as pharmaceutical manufacturers.