Research Progress of Anti-inflammatory Effects and Molecular Mechanism of Ginsenosides / 中国药学杂志

ABSTRACT

The anti-inflammatory effects of ginsenosides in the past ten years and the molecular mechanisms of anti-inflammatory effects were reviewed in this paper. The main pharmacological active component of ginseng is ginsenoside and it had been proved to be effective in many diseases. The application of ginsenoside in inflammatory diseases was mainly introduced. The anti-inflammatory mechanism of ginsenoside mainly includes three aspects ①anti-oxidation effect; ②effects on inflammatory factors and inflammatory signaling pathways; ③effects on intestinal flora. Ginseng is a great tonic for vitality and health, This article provides scientific basis for further pharmacological activity study of ginsenoside, and for the development of new anti-inflammatory drugs with high curative effect and low toxic side effect, It also provides scientific basis for the clinical applications.