Research Progress of Liquid Crystalline Nanoparticles as Drug Delivery System / 中国药学杂志

ABSTRACT

Liquid crystalline nanoparticles are composed of a certain concentration of amphiphilic lipid self-assembly in water. The attractiveness of this formulation is linked to the nanostructural versatility, compatiblity, digestiblity and bioadhesive properties of their lipid constituents, and the capability of solubilizing and sustaining the release of amphiphilic, hydrophobic and hydrophilic drugs. Liquid crystalline nanoparticles, as a novel drug delivery system, have great promise in drug delivery. The carrier materials, preparation methods, characterization and applications of liquid crystalline nanoparticles were reviewed based on relevant articles published in recent years to provide reference for further study of liquid crystal nanoparticles.