Liposoluble Constituents of Urticae Rhizoma / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 1217-1222, 2017.
Article
em Zh
| WPRIM
| ID: wpr-858638
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ABSTRACT
OBJECTIVE: To investigate the liposoluble constituents of Urticae Rhizoma. METHODS: The compounds were isolated and purified by silica gel, Sephadex LH-20, ODS gel column chromatographies, and semi-preparative HPLC. The structures were elucidated on the basis of spectral data and physiochemical properties. RESULTS: Twenty-one compounds were isolated from the ethyl acetate fraction of Urticae Rhizoma, and identified as(-)-urticol(1),(-)-secoisolariciresinol(2), 23-hydroxybetulinic acid(3), 2α,3β, 24-trihydroxy-12-oleanen-28-oic acid(4), cleomiscosin A (5), dihydro-4-hydroxy-5-hydroxymethyl-2(3H)-furanone(6), methyl chlorogenate(7), kaempferol(8), pinoresinol monomethyether-4'-O-β-D-glucopyranoside(9), martairesinol-4'-O-β-D-glucopyranoside(10), cycloolivil-6-O-β-D-glucopyranoside(11), stigmasterol-3-O-β-D-glucopyranoside(12), nicotinamide(13), trans-caffeic acid-4-O-β-D-glucopyranoside(14), esculin(15), 5-hydroxyl-7-methoxycoumarin-8-O-β-D-glucopyranoside(16), 6-oxymethyluteolin-7-O-β-D-glucopyranoside(17), luteolin-7-O-β-D-glucopyranoside(18), quercetin-3-O-(4″-methoxy)-α-L-rhamnopyranoside(19), 2'-deoxy uridine(20), and apigenin-6, 8-di-C-β-D-glycoside(21), respectively. CONCLUSION: All the compounds, except 8 and 12, are isolated from U. fissa for the first time. Meanwhile, compounds 5, 6, 9, 10, 11, 14, 16, 17, and 19 are all found in Urticaeae plants for the first time.
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WPRIM
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Zh
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2017
Tipo de documento:
Article