Chemical Constituents of Inula cappa / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of Inula cappa. METHODS: Chromatographic techniques were employed for isolation and purification of the constituents and their structures were determined by spectral analysis and chemical evidence. RESULTS: Seventeen compounds were obtained and identified as friedelin(1), epifriedelanol(2), α-amyrin(3), β-amyrin(4), benzyl 2-O-β-D-glucopyranosy-2, 6-dihydroxybenzoate(5), scopoletin(6), luteolin-7-O-β-D-glucuronide ethyl ester(7), benzyl alcohol glucoside(8), ophiopogonoside A(9), apigenin-7-O-β-D-glucoside(10), luteolin-7-O-β-D-rutinoside(11), hydnocarpin-D(12), luteolin(13), luteolin-7-O-β-D-glucoside (14), luteolin-4'-O-β-D-glucoside (15), quercetin-3-O-β-D-glucoside (16), and juglans cerebroside A(17). CONCLUSION: Compounds 5, 7, 9, 11, 12, and 17 are for the first time obtained from the genus Inula and compounds 8, 10, 14, and 16 are isolated from Inula cappa for the first time.