A review of monitoring methods of non-vitamin K antagonist oral anticoagulants / 中国药学杂志

ABSTRACT

Both laboratory monitoring and point-of-care testing (POCT) are the major two methods for monitoring of non-vitamin K antagonist oral anticoagulants. The safety interval of laboratory testing has not been estalished for surveillance and management of bleeding risk associated with NOACs, even though some sensitive measurements of the effects of these novel drugs have already been identified. Only a few studies investigated the effects of POCT, but most of them have positive results. Both laboratory monitoring and POCT are necessary to be evaluated in large clinical studies in patients receiving treatment with non-vitamin K antagonistoral anticoagulants. This paper reviews the latest research on monitoring non-vitamin K antagonist oral anticoagulants (NOACs).