Chemical constituents of Semen Sojae Praeparatum and their proliferation activity on rat osteoblasts / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 203-206, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-859221
ABSTRACT
OBJECTIVE:
To study the chemical constituents and their proliferation activity on rat osteoblasts of Semen Sojae Praeparatum.METHODS:
The compounds were isolated by chromatography on silica gel column, MCI and sephadex LH-20 column. Their structures were elucidated by spectral analysis. The proliferation test was performed by using rat osteoblasts with MTT assays in vitro.RESULTS:
Twelve compounds were obtained and identified as daidzin(1), daidzein(2), genistein(3), genistin(4), glycitein(5), glycitin(6), apigenin(7), β-sitosterol(8), stigmasterol(9), campesterol(10), syringaldehyde(11), syringic acid(12), respectively.CONCLUSION:
Compounds 5-11 are isolated from Semen Sojae Praeparatum for the first time. The five isoflavones show proliferation activity on rat osteoblasts, and aglycones proved to show better activity than glycosides.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2016
Tipo de documento:
Artigo
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