Research status of activatable cell-penetrating peptides-modified nanocarrier systems / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 2015-2018, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-859276
ABSTRACT
Activatable cell-penetrating peptides (ACPPs) is a new-type targeted delivery system, composed of cell-penetrating peptides, environmentally-sensitive (or stimuli-responsive) linker and shielding peptides, allowing cell-penetrating peptides high membrane permeability in specific environment or to specific stimulus, reducing systemic toxicity resulting from non-specific cellular uptake. To enhance the tumor selectivity of carriers, investigators combine ACPPs and nanocarriers in researches on cancer detection and treatment by delivering molecular probes and therapeutic agents (anticancer drugs and genes), and so on. This paper makes an overview about the reported ACPPs-modified nanocarrier systems in the recent decade.
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Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2015
Tipo de documento:
Artigo
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