A Case of Churg-Strauss Syndrome with Renal and Gastrointestinal Involvement / 대한피부과학회지

ABSTRACT

Churg-Strauss syndrome is a systemic necrotizing vasculitis occurring in patients with asthma or allergic rhinitis, and characterized by eosinophilic infiltration of various tissues and peripheral eosinophilia. A 28-year-old male was admitted due to painful purpuric papules and patches on both lower legs and both hands with dysesthesia and weakness for 4 days. He had been well until 8 months earlier when asthma developed. Abnormal laboratory findings including peripheral blood eosinophilia, p-ANCA(+), elevated BUN and creatinine, hematuria, proteinuria, and stool occult blood were observed. Parenchymal renal disease of both kidneys was confirmed by abdominal sonogram. Marked muscular atrophy in the first web space of left hand dorsum and difficulty in dorsiflexion of both feet had developed, suggesting mononeuritis multiflex in bilateral peroneal and tibial nerves, left ulnar and radial nerves.