Flavonoid constituents of leaves of Ampelopsis grossedentata (Hand-Mazz) W.T. wang / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of Ampelopsis grossedentata (Hand-Mazz) W.T. wang. METHODS: The chemical constituents were isolated and purified with silica column chromatography, gel chromatography, etc. Their structures were identified by physicochemical properties and various spectroscopic methods including NMR spectrum, MS, UV, etc. RESULTS: Sixteen compounds were isolated and elucidated as dihydromyricetin(1), physcion(2), quercetin(3), myricetin(4), taxifolin(5), kaempferol(6), dihydrokaempferol(7), myricetin-3-O-L-rhamnoside(8), afzelechin(9), bellidifod-in(10), quercetin-3-O-α-L-rhamnopyranoside(11), myricetin-3'-O-β-D-xylopyranoside(12), ampelopsin(13), myricetin-3-O-β-D-glucoside(14), astragalin(15) and myricetin-3-O-β-D-galactopyranoside(16). CONCLUSION: Compound 10 is reported from the plants in genus Ampelopsis for the first time. Compounds 5,6,7,9,12 and 15 are isolated from this plant material for the first time.