Analysis of clinical characteristic and drug therapy in elderly chronic heart failure patients / 中国药学杂志

ABSTRACT

OBJECTIVE: To investigate the clinical characters and the situation of oral drug therapy in elderly chronic heart failure patients. METHODS: The survey was conducted among 68 chronic heart failure patients who were hospitalized between October 2013 and October 2014 in Peking university people's hospital. Data were collected and statistically analyzed concerning the clinical characters and the oral drug therapy between the elderly and non-elderly groups. RESULTS: Worsening of heart function was more significantly in the elderly chronic heart failure group than the non-elderly group. There was a tendency of multiorgan statement represented by hepatic and renal function to decrease with age. Both the level of serum and the percentage of those proper for beta blocker arrived to the minimal target dose were lower in the elderly group than in the matched group. Combined treatment of different drug was more common in the elderly group. CONCLUSION: The physiological functions of elderly patients decreased and the patients often had many concomitant disease. It is very important to pay more attention to drug selections, drug interactions and adverse reactions to optimize the treatment plan to improve the quality of life and the prognosis of these elderly chronic heart failure patients according their clinical characters.