Progress in the chemical synthesis of artemisinin / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 795-805, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-859716
ABSTRACT
OBJECTIVE:
To introduce the research progress in total-and semi-synthesis of artemisinin.METHODS:
The review was based on representative literatures, and the data was summarized and analyzed. RESULTS ANDCONCLUSION:
Artemisinin is one of the most effective anti-malarial medicines. Since its discovery, artemisinin chemical synthesis has become a hot research topic. Nine total-synthesis methods andfive semi-synthesis methods were summarized, for which the overall yields were up to 10% and 60% respectively. Efficient synthesis of artemisinin in large scale by industry would be realized in the near future, and it will benefit hundred millions of patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2014
Tipo de documento:
Artigo
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