Analysis of chemical constituents of volatile oils from Artemisia mongolica and their antimicrobial activities / 中国药学杂志

ABSTRACT

OBJECTIVE: To analyze the chemical components of volatile oil from Artemisia mongolica by GC/MS, and to investigate their antimicrobial activities. METHODS: The volatile oils were extracted from Artemisia mongolica by SFE-CO2 technique, their chemical components were analyzed by GC/MS, and their antimicrobial activities were tested by agar plate diffusion method. RESULTS: Twenty-eight compounds were separated from the crude essential oils and 23 compounds were identified. The bacteriostatic experiment results indicated that this volatile oil has strong inhibitory effects on Staphyloccocus albus, Shigella flexneri and Bacillus paratyphosus B, whereas it had no remarkable effect on Staphyloccocus aureus. CONCLUSION: The experiment provides a scientific basis for further development and utilization of Artemisia mongolica.