Comparison and development trend analysis of potency test methods of adsorbed tetanus vaccine / 中国药学杂志

ABSTRACT

OBJECTIVE: To get the present information of potency assay Methods of adsorbed tetanus vaccine, latest research and developmental trend. METHODS: Induction, summary and analyses were used, mainly according to the Chinese Pharmacopoeia, European Pharmacopoeia, British Pharmacopoeia, Japanese Pharmacopoeia, Indian Pharmacopoeia, the manual for quality control of diphtheria, tetanus, and pertussis vaccines, adopted Methods of FDA and literatures in the field. RESULTS and CONCLUSION: In the near future, complete in vitro potency assay Methods of adsorbed tetanus vaccine can be used instead of in vivo assay, so it is important and urgent that related research should be made in China.