Chemical constituents of rhizome of Dasymaschalon trichophorum Mer / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of Dasymaschalon trichophorum Mer. METHODS: The chemical constituents were isolated and purified by silica gel, Sephadex LH-20, and recrystallization. Their structures were elucidated by spectral analysis and physicochemical properties. RESULTS: Ten compounds were obtained from petroleum ether fraction, ethyl acetate fraction and chloroform fraction of water extraction of Dasymaschalon trichophorum Mer. They were identified as 5-methoxydasytrichone(1), (2R, 3R)-3, 5, 7, 3', 4'-pentahydroxyflavane(2), dasytrichone(3), 3, 4, 5-trimethoxyphenol-β-D-glucopyranoside(4), N-trans-caffeoyltyramine(5), 1', 4-dihydroxy-3, 3', 5'-trimethoxy-8, 4'-oxyneoligna-7, 9-diol(6), resveratrol(7), naringetol(8), dihydrokaempferol(9) and eriodictyol(10). CONCLUSION: Compounds 1, 2, 4, 5, 6, 7, 8, 9 and 10 are isolated from Dasymaschalon trichophorum Mer for the first time.