Comparison on imaging and pathological features of adenosquamous carcinoma of pancreas and invasive ductal adenocarcinoma of pancreas / 中国医学影像技术

ABSTRACT

Objective: To comparatively analyze CT, MRI and pathological findings of adenosquamous carcinoma of pancreas (ASqC) and invasive ductal adenocarcinoma of pancreas (IDAC). Methods: Clinical, imaging and pathological data of 11 patients with ASqC (ASqC group) and 22 with IDAC (IDAC group) confirmed with pathology were retrospectively analyzed. The differences of imaging findings (lesion location, size, morphology, central necrosis, peak enhancement time, bile duct dilatation, main pancreatic duct dilatation) and pathological features (nerve tract invasion, lymph node metastasis, vascular tumor emboli, Ki-67) were compared between 2 groups. Results: CT showed significant differences in lesions' diameter, morphology, central necrosis and peak enhancement time between 2 groups (χ2=7.34, 6.82, 10.25, 5.57, all P<0.05). MRI showed that there was no significant difference of lesion's signal on T1WI and dynamic enhancement between 2 groups, while IDAC group had lower T2WI signals than ASqC group. Pathological results showed that the incidence of vascular tumor emboli in ASqC group (5/11, 45.45%) was higher than that in IDAC group (2/22, 9.09%, χ2=5.80, P=0.02). Conclusion: ASqC and IDAC have certain pathological and imaging characteristics. Combination with clinical data is helpful to differential diagnosis.