18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice helical CT in diagnosis of solitary pulmonary nodules / 中国医学影像技术

ABSTRACT

Objective: To explore the value of 18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT in diagnosis of solitary pulmonary nodules (SPN). Methods: A total of 139 patients with SPN were selected. After routine 18F-FDG PET/CT scanning, thin-slice spiral CT scanning and three-dimensional reconstruction were performed. The accuracy of single 18F-FDG PET/CT and 18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT in diagnosis of SPN were recorded and compared. Results: Totally 139 SPN were pathologically confirmed after operation or puncture, including 83 malignant and 48 benign ones. SPN in 8 patients became small or disappeared after clinical anti-inflammatory treatment, and thus were diagnosed as benign ones. The sensitivity, specificity and coincidence rate of combined diagnosis of SPN nodules was 85.71% (72/84), 78.18% (43/55) and 82.73% (115/139), respectively, all higher than of single 18F-FDG PET/CT (64.29% [54/84], 54.55% [ 30/55] and 60.43% [84/139], respectively). Conclusion: 18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT can significantly improve the accuracy for diagnosing SPN. [Keywords] solitary pulmonary nodules; positron-emission tomography; thin-slice scanning; three-dimensional reconstruction