Application of intraoperative ultrasound combined with neuronavigation in microsurgery of low-grade glioma / 中国医学影像技术

ABSTRACT

Objective: To explore the application value of intraoperative ultrasound (IOUS) combined with neuronavigation in the microsurgery of low-grade glioma (LGG). Methods Totally 34 patients with LGG underwent microsurgery assisted by IOUS combined with neuronavigation. The degree of tumor resection was evaluated by MRI within 72 hours after operation. Occurrence of IOUS related adverse events such as brain contusion, cerebral hemorrhage and complications such as intracranial infection and cerebral hematoma were observed. Results: The detection rate of tumors by IOUS combined with neuronavigation was 100% (34/34) and accuracy rate of localization was 100% (34/34) in the 34 LGG patients. MRI within 72 hours after operation showed total resection in 27 cases (27/34, 79.41%), subtotal resection in 3 cases (3/34, 8.82%), and partial resection in 4 cases (4/34, 11.76%). Intracranial infection occurred in 2 cases which were improved after anti-infection treatment, but no IOUS scan related adverse events occurred. Conclusion: IOUS combined with neuronavigation can accurately locate LGG and achieve maximum extent safely resection of tumors.