3D speckle tracking imaging in evaluating severity of coronary artery disease / 中国医学影像技术

ABSTRACT

Objective: To explore the value of 3D speckle tracking imaging (3D-STI) in evaluating the degree of coronary artery disease in patients with coronary artery disease. Methods Totally 103 patients with suspected coronary artery disease were enrolled. According to the coronary angiography results and Gensini score, the patients were divided into lesion group (n=79) and normal group (Gensini score=0, n=24). Patients in lesion group were then divided into mild subgroup (Gensini score 50, n=13). 3D global longitudinal strain (3D-GLS), 3D global circumferential strain (3D-GCS), 3D global area strain (3D-GAS) and 3D radial strain (3D-GRS) were obtained using 3D-STI and compared between the two groups and among the three subgroups. ROC curve was drawn, and the efficacy of 3D-STI parameters were evaluated for the normal or mild coronary lesions (Gensini score <25) and moderate to severe lesions (Gensini score ≥25). Results: 3D-GLS, 3D-GCS, 3D-GAS and 3D-GRS in the lesion group were lower than those in the normal group (all P<0.05). There were significant differences in the overall strain parameters among the mild, moderate and severe subgroups in the lesion group (all P<0.05). ROC curve results showed that AUC decreased from 3D-GLS (0.929), 3D-GCS (0.873), 3D-GRS (0.853) to 3D-GAS (0.819). Conclusion: 3D-STI has certain value in evaluating the severity of coronary artery disease in patients with coronary artery disease.