Comparison of diagnostic performances of ultrasonography and digital breast tomosynthesis in dense breasts / 中国医学影像技术

ABSTRACT

Objective To compare the diagnostic performances of ultrasonography and digital breast tomosynthesis (DBT) in women with dense breasts. Methods A total of 148 women (148 breast lesions) with dense breasts underwent DBT and ultrasonography. Then the patients were divided into groups according to the composition of the breast, patients' age, lesion size and with or without calcification. Taking pathological results as gold standards, ROC curve was used to evaluate the diagnostic performances of ultrasonography DBT, and the AUC, sensitivity and specificity of them were compared. Results AUC of ultrasonography and DBT in diagnosis of dense breast lesions was 0.956 and 0.815 (Z=3.866, P40-55 years (0.946 vs 0.801, P=0.013) groups. According to clinical diagnostic criteria, the sensitivity of ultrasonography and DBT in diagnosis of benign and malignant lesions in dense breast was 94.32% (83/88) and 93.18% (82/88, χ2=0.096, P=1.000), and the specificity was 83.33% (50/60) and 61.67% (37/60, χ2=7.060, P=0.007). Conclusion Ultrasonography shows better diagnostic performance than DBT in women with dense breast. Ultrasonography is suitable to be chosen as the preferred examination in women with small lesions in heterogeneously dense breasts and aged ≤55 years than DBT.