Mechanism of Effect of Ubiquitination Modification Mediated by E3 Ubiquitin Ligase in Inflammatory Bowel Disease / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 250-253, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-861696
ABSTRACT
Ubiquitination is the important type of post-translational modification of proteins, and its main effects include protein degradation and functional regulation. Studies have shown that abnormal ubiquitination is involved in the development and progress of inflammatory bowel disease (IBD), which makes some ubiquitinases and their antibodies having the potential to be important markers for clinical diagnosis and evaluation of severity of Crohn's disease (CD). This article reviewed the research on mechanism of effect of ubiquitination modification mediated by E3 ubiquitin ligase in IBD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Gastroenterology
Ano de publicação:
2020
Tipo de documento:
Artigo
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