Research Progress and Prospects in Targeted Therapy for Colorectal Cancer / 胃肠病学

ABSTRACT

Targeted drug combined with chemotherapy have become the trend in treatment of advanced colorectal cancer, one of the most common cancers worldwide. To date, nearly ten targeted drugs have been approved for clinical use, helping to extend patients' lifetime by months or even years. Meanwhile, with the exploration in etiology and molecular pathogenesis, new targeted drugs come forth continuously. However, problems remain in various aspects, such as ways to dealing with drug resistance, individualized drug choice and treatment decisions. This review article described the achievements and challenges in targeted therapy for colorectal cancer.