Research Progress of Peutz-Jeghers Syndrome / 胃肠病学

ABSTRACT

Peutz-Jeghers syndrome (PJS) is an autosomal dominant inheritance disease with tumor susceptibility and characterized by skin mucosal pigmentation, multiple gastrointestinal polyps and positive family history, and its pathogenetic gene is the STK11 gene located at 19p. The disease is rare in China. This article reviewed the current status of research on pathogenesis, clinical features, diagnosis and treatment of PJS.