Intestinal Microbiota and Irritable Bowel Syndrome: Basic and Clinical Study / 胃肠病学

ABSTRACT

The relationship between intestinal microbiota and functional gastrointestinal disorders (FGIDs) has become one of the hottest topics. The latest Rome criteria states that FGIDs have been more than just gastrointestinal disorders, and that abnormal brain-gut interaction may persist throughout the onset of irritable bowel syndrome (IBS). Intestinal dysbiosis is considered to be an important initiating factor leading to disorder of brain-gut interaction, constituting the microbiota-gut-brain axis, which has become a new research hotspot. Especially in the study of IBS, the intestinal dysbiosis has been confirmed to be related to IBS immune abnormalities and clinical symptoms. Using probiotics to regulate intestinal flora of IBS has achieved good efficacy, and other intestinal flora intervention strategies are being explored.