Advances in Research on Eosinophilic Esophagitis / 胃肠病学

ABSTRACT

Eosinophilic esophagitis (EoE) is a chronic, local immune-mediated esophageal disease, characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation. The incidence and prevalence are increasing rapidly in recent years. Children often present with symptoms and endoscopic patterns of inflammation, whereas most adolescents and adults have manifestations of esophageal fibrosis and stricture. Clinical and endoscopic scoring systems are helpful for standardizing the disease assessment. There is controversy over the optimal treatment endpoint of EoE. Clinicians should improve their understanding of EoE and its progression for effective diagnosis, assessment and treatment of the disease.