Role of Bacteroides fragilis in Colorectal Diseases and Prospect of Microflora Therapy / 胃肠病学

ABSTRACT

Bacteroides fragilis (BF) is a symbiotic bacterium in human intestine, and has a variety of effect on intestinal environment. BF can be divided into enterotoxigenic Bacteroides fragilis (ETBF) and nontoxigenic Bacteroides fragilis (NTBF). ETBF can lead to diarrhea, colitis, inflammatory bowel disease and colorectal cancer, while NTBF has a protective effect on intestinal homeostasis. NTBF not only can provide nutritional support for other microorganisms, but also enhance the anti-inflammatory effect of immune cells. This article reviewed the effect of BF on colorectal diseases and prospect of microflora therapy.