CT and MRI features of hepatic sinusoidal obstruction syndrome / 中国介入影像与治疗学

ABSTRACT

Objective: To observe CT and MRI features of hepatic sinusoidal obstruction syndrome (HSOS). Methods: Clinical and imaging data of 45 HSOS patients were retrospectively analyzed. Results: Forty-one patients underwent CT examination. Plain CT showed liver enlargement in 20 cases, including enlargement of left lobe and caudate lobe in 7 cases. Decreased density of liver parenchyma was observed in 21 cases, different degrees abdominal effusion in 36 cases, and pleural effusion in 2 cases. Contrast-enhanced CT scan showed uneven enhancement of liver parenchyma in 31 cases, map-like enhancement in 21 cases, patchy uneven enhancement in 9 cases and minor enhancement in 1 case. Patchy map-like enhancement of the portal venous phase was detected in all patients, and the enhancement range further expanded during delayed phase. No bile duct dilatation nor angiogenesis of the medial and lateral hepatic branches was observed. Twelve patients underwent MR examination. Plain MRI showed uneven liver signals, the liver enlargement in 10 cases, and compressed and tapered posterior segment of inferior vena cava in 5 cases. No morphologic abnormality of gallbladder was found in 12 cases. Enhanced MRI showed uneven enhancement of liver parenchyma, and the reduced area of lamellar enhancement and abnormal enhancement foci were all map-shaped. Conclusion: CT and MRI manifestations of HSOS have certain characteristics, which are helpful for clinical diagnosis.