Analysis of outcome of fetuses with dilated fetal cavity of septum pellucidum detected with prenatal ultrasonography / 中国介入影像与治疗学

ABSTRACT

Objective: To analyze the outcome of fetuses with dilated fetal cavity of septum pellucidum (CSP), and to explore the clinical significances of dilated CSP detected with prenatal ultrasonography. Methods: Fetuses with dilated CSP detected with prenatal ultrasonography were followed up, and the results of prenatal imaging examination and perinatal outcomes were recorded. Results: Totally 48 fetuses were found with dilated CSP using prenatal ultrasound, among them 9 were lost during follow-up and 39 were enrolled in the study, including 13 with isolated dilated CSP and 26 with accompanied other abnormalities. Chromosome analysis was performed in 11 fetuses, and 2 were found abnormal. Induced labor was performed in 6 fetuses with various deformities. One fetus died intrauterine at 38 weeks of pregnant for unknown cause, 2 newborns died several days after delivery, while postnatal motor and cognitive developmental delay were observed in 1 case. During 3-46 months' follow-up, 29 cases (including 13 with isolated dilated CSP and 16 dilated CSP accompanied with other mild abnormalities) showed no significant abnormalities compared with their peers after birth. Conclusion: The outcome of fetuses with isolated dilated CSP detected with prenatal ultrasonography is good, and the prognosis of those with other malformations depends on the severity of the accompanying malformations.