Clinical effectiveness and safety of HIFU in ablation of uterine fibroids with different MR T2WI signals / 中国介入影像与治疗学

ABSTRACT

Objective: To investigate the ablation effect and safety of HIFU for uterine fibroids with different MR T2WI signals. Methods: Totally 156 patients with 210 uterine fibroids were treated with HIFU ablation. According to preoperative MR T2WI performances, uterine fibroids were divided into low signal group, equal signal group, high signal group and mixed signal group. The preoperative fibroid volume and intraoperative therapeutic dose parameters (sound source power, irradiation time, therapeutic dose and treatment intensity), energy efficiency factor, postoperative ablation rate, fibroid reduction, as well as the incidence of intraoperative and postoperative adverse reactions were compared among 4 groups. Results: There were statistical differences of preoperative fibroid volume (χ2=14.720, P=0.002), irradiation time (F=10.422, P0.05). Conclusion: HIFU treatment is safe and effective for uterine fibroids with different signals of MR T2WI. However, uterine fibroids with high signals on MR T2WI are difficult to ablate, and the postoperative efficacy is relatively poor.