Comparison between ct-guided microwave ablation and cryoablation in treatment of malignant pulmonary tumors / 中国介入影像与治疗学

ABSTRACT

Objective: To compare the efficacy and safety of microwave ablation and cryoablation in treatment of malignant pulmonary tumors. Methods: A retrospective analysis was performed on 48 patients with primary or metastatic pulmonary malignant tumors who underwent CT-guided ablation, among them 29 were treated with microwave ablation (microwave ablation group) and another 19 received cryablation (cryablation group). Statistical analysis was used to compare the incidence of postoperative complications, the rate of effectiveness ablation, the rate of disease control and the survival rate between the two groups. Results: There was no statistical difference of the incidence of postoperative complications between microwave ablation group and cryoablation group (34.48% [10/29] vs 42.11% [8/19]; χ2=0.285, P=0.594). No statistical difference of the rate of effectiveness ablation (72.41%% [21/29] vs 73.68% [14/19]; χ2=0.009, P=0.923)nor the rate of disease control (96.55% [28/29] vs 94.74% [18/19]; χ2=0.095, P=0.758) was found 3 months after ablation. The survival rate at 6, 12, 24 and 36 months after treatment was 92.72%, 81.28%, 64.54% and 54.91% in microwave ablation group, and 94.07%, 81.13%, 57.33% and 43.04% in cryablation group, respectively. There was no statistical difference of survival rate between the two groups (P=0.793). Conclusion: CT-guided microwave ablation and cryoablation are both effective and relatively safe for treatment of malignant pulmonary tumors.