Changes of immune function in children with severe mycoplasma pneumoniae pneumonia / 国际儿科学杂志

ABSTRACT

In recent years, the incidence of mycoplasma pneumoniae pneumonia (MPP) has gradually increased, and in infant population, it has an increasing trend.The proportion of severe mycoplasma pneumoniae pneumonia (SMPP) has also increased relatively.In addition to causing respiratory symptoms, SMPP is also prone to complicating extrapulmonary complications, accumulating serious diseases such as the circulatory system, nervous system, blood system, and digestive system, which seriously affect children′s health.Researchers at home and abroad have done a lot of research on its pathogenesis, and found that its pathogenesis is not completely clear, but it is closely related to immune disorders, mainly including immunoglobulin, T lymphocyte subsets, complement, cytokines, affecting the occurrence, development and prognosis of SMPP.Pediatricians should be familiar with changes it′s immune function and then combine clinical manifestations, to make early diagnosis and treatment to improve the prognosis of children.This article reviews the changes of immune function in SMPP.