Progress in the pathogenesis of Henoch-Sch?nlein purpura nephritis and IgA nephropathy in children / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 569-572, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-863021
ABSTRACT
Henoch-Sch?nlein purpura nephritis and IgA nephropathy are both characterized by extensive deposition of IgA in the mesangial area.In recent years, the researches on the pathogenesis of the two diseases have made significant progress.It was confirmed that the pathogenesis included the aberrantly glycosylated IgA1, abnormal complement activation, cellular immune imbalance and cytokine production disorder, genetic factors and so on.Furthmore, some other immunopathogenic mechanisms have a breakthrough on endothelial cell particles, extracellular trapping nets, podocyte autophagy and abnormal peptide lineage, offering new ideas for diagnosis and treatment of disease.This paper will review the above pathogenesis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de etiologia
Idioma:
Chinês
Revista:
International Journal of Pediatrics
Ano de publicação:
2020
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS