Application of flow cytometry analyzing basophil activation test in allergy disease / 国际儿科学杂志

ABSTRACT

Allergic disease is the common disease that affects human health and life quality.With the development of flow cytometry, basophil activation test(BAT), as an ex vivo challenge test, has become a new method in the diagnosis of allergic disease that IgE mediates.An important step is to establish a standardized BAT method in order to make it available in clinical applications and to explore the mechanisms of allergy in laboratory.This review focuses on the main principles, clinical utility in the diagnosis and management of allergic disease.