Design of a portable nitric oxide rescue device / 国际生物医学工程杂志

ABSTRACT

Objective:To design a portable NO rescue device that can be used for NO inhalation therapy.Methods:The NO rescue device adopts a modular design, and the key parameters can be easily adjusted. The device uses a low-intensity, high-frequency pulse discharge method to produce NO mixed gas by ionizing dry air at atmospheric pressure, and uses Ca(OH) 2 particles to filter the NO 2 gas in the NO mixed air. Based on the NO rescue device, the effects of airflow direction, gas flow rate and input voltage on the levels of NO and NO 2 in the NO mixed gas were studied. The NO 2 filtering performance of the NO 2 removal device in the device was also studied. Results:When the air flows in from the cathode and flows out from the anode of the reaction chamber, and the flow rate and input voltage respectively were 2 L/min and 4 V, the system had a better performance. At this condition, the volume fraction of NO in the output gas is 3.25×10 -5, and NO 2/NO is about 0.05. Conclusions:The proposed NO rescue device can meet the needs of medical NO gas, and the system has stable performance, portable volume, and low cost, and has broad application prospects in the treatment of pulmonary hypertension and chronic obstructive pulmonary diseases.