Clinical features of irritable bowel syndrome in children / 中华实用儿科临床杂志

ABSTRACT

Objective:To investigate the clinical features of children with irritable bowel syndrome(IBS), so as to achieve the early diagnosis and treatment, thus avoiding misdiagnosis and mistreatment.Methods:A total of 80 hospitalized IBS patients in the Department of Gastroenterology, Children′s Hospital of Chongqing Medical University from January 2012 to August 2018 were enrolled.Their diagnosis and treatment were analyzed by combining with literature reviews.Results:(1)A total of 80 cases include 53 boys and 27 girls.The mean age at diagnosis was(9.70±2.88)years, and the median duration of disease was 10 months.(2)Abdominal pain was found in all cases, followed by diarrhea in 60 cases, constipation in 31 cases, abdominal distension in 21 cases, vomiting in 19 cases, weight loss in 11 cases, loss of appetite in 9 cases, and headache in 3 cases.Twenty-nine cases had suspected triggers before onset, mostly diet factor.(3)Eighty cases with IBS include 46 cases with irritable bowel syndrome with diarrhea(IBS-D), 17 cases with irritable bowel syndrome with constipation(IBS-C), 13 cases with mixed irritable bowel syndrome(IBS-M) and 4 cases with unsubtyped irritable bowel syndrome(IBS-U). The number of boys with IBS-C and IBS-D was higher than that of girls.IBS-M was on the contrary.IBS-U was equal between them.There were significant differences in gender among the subtypes ( χ2=0.83, P=0.001). Abdominal distension among 4 clinical types was statistically diffe-rent, IBS-M had the highest incidence, followed by were IBS-C, IBS-D, IBS-U.(4)Treatment was aimed at patients education, psychological intervention, dietary management and symptomatic therapy.After the first 6 months visit of 74 cases, 34 cases were sustained relieved, 25 cases were alleviated, and the overall effective rate was 79.73%, but 15 cases were ineffective. Conclusions:IBS is a common functional gastrointestinal disease in children, with more boys than girls.Dietary stimulation is the most common cause.Among the 4 subtypes, the composition ratio of IBS-D is the highest.Most of the cases are effective in symptomatic treatment.There are still some patients with poor curative effect.