Clinical research of early comprehensive intervention for development of premature infant / 中国医师进修杂志

ABSTRACT

Objective:To research the clinical effect of early comprehensive intervention for physical and intelligence development of premature infant (test-tube baby).Methods:One hundred and eleven premature infant in Dalian Municipal Women and Children′s Medical Center from June 2016 to June 2018 were enrolled. Study group (57 cases) received comprehensive intervention including health education, exercise training, nutrition guidance and rehabilitation therapy, and control group (54 cases) received health education. The weight, height, head circumference and CDCC score of two groups were analyzed in 3, 6 and 12 month.Results:Physical development the weight [3 month (4.72 ± 0.19) kg vs. (4.34 ± 0.29) kg; 6 month (6.49 ± 0.37) kg vs. (6.25 ± 0.41) kg; 12 month (9.58 ± 1.15) kg vs. (8.76 ± 0.92) kg] and height [3 month (59.63 ± 5.51) cm vs. (56.29 ± 5.86) cm; 6 month (65.09 ± 5.94) cm vs. (62.36 ± 6.20) cm] in 3, 6 and 12 month, and head circumference in 3 and 6 month [3 month (37.71 ± 1.77) cm vs. (35.90 ± 1.48) cm; 6 month (43.18 ± 1.96) cm vs. (41.82 ± 2.61) cm] of study group were higher than those in control group, and all difference had statistical significant ( P<0.05). Intelligence development the MDI [3 month (84.49 ± 9.78) scores vs. (80.58 ± 10.40) scores; 6 month (89.65 ± 13.21) scores vs. (83.24 ± 17.66) scores; 12 month (96.03 ± 15.43) scores vs. (89.71 ± 17.85) scores] and PDI score of study group was higher than that in control group in 3, 6 and 12 month [3 month (82.68 ± 5.35) scores vs. (79.43 ± 7.21) scores; 6 month (86.34 ± 8.33) scores vs. (82.51 ± 9.67) scores; 12 month (94.86 ± 10.27) scores vs. (90.32 ± 11.65) scores] ( P<0.05). Conclusions:Early comprehensive intervention has a good clinical efficacy for physical and intelligence development of premature infant (test-tube baby) and is worthy of popularizing and applying.