The Roles of Innate Lymphoid Cells in the Development of Asthma
Immune Network
; : 171-181, 2014.
Article
em En
| WPRIM
| ID: wpr-86713
Biblioteca responsável:
WPRO
ABSTRACT
Asthma is a common pulmonary disease with several different forms. The most studied form of asthma is the allergic form, which is mainly related to the function of Th2 cells and their production of cytokines (IL-4, IL-5, and IL-13) in association with allergen sensitization and adaptive immunity. Recently, there have been many advances in understanding non-allergic asthma, which seems to be related to environmental factors such as air pollution, infection, or even obesity. Cells of the innate immune system, including macrophages, neutrophils, and natural killer T cells as well as the newly described innate lymphoid cells, are effective producers of a variety of cytokines and seem to play important roles in the development of non-allergic asthma. In this review, we focus on recent findings regarding innate lymphoid cells and their roles in asthma.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Asma
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Linfócitos
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Citocinas
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Interleucina-5
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Células Th2
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Poluição do Ar
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Células T Matadoras Naturais
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Imunidade Adaptativa
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Sistema Imunitário
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Pneumopatias
Idioma:
En
Revista:
Immune Network
Ano de publicação:
2014
Tipo de documento:
Article