Research progress on radiation-resistant and radiation-sensitive proteomics in glioma stem cells / 中华放射肿瘤学杂志
Chinese Journal of Radiation Oncology
;
(6): 150-153, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-868568
ABSTRACT
After multidisciplinary treatment including radiotherapy,the median survival of patients with glioblastoma multiforme (GBM) remains approximately 1 year.The heterogeneity of the genome and proteome of glioblastoma stem cells (GSC) is the fundamental factor affecting the prognosis.Proteomics-based sensitization of key radioresistance proteins is expected to improve the prognosis of GBM patients.In this article,literature review was conducted from PubMed and other databases in the previous 10 years to systematically discuss the research progress on various commonly used protein quantitative techniques,tools for data processing analysis and the application in radioresistance and radiosensitization of GSCs.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Journal of Radiation Oncology
Ano de publicação:
2020
Tipo de documento:
Artigo
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