Delineation of prophylactic cervical target volumes in radical radiotherapy for supraglottic laryngeal carcinoma / 中华放射肿瘤学杂志

ABSTRACT

Intensity-modulated radiotherapy (IMRT) is one of the primary treatments for laryngeal cancer. According to the latest international guidelines, the delineation of lymphatic clinical target volumes (CTV) is performed only on the basis of N stage without considering other impact factors, such as tumor subsite, clinical stage and histopathological differentiation. Besides, the detailed lymph node regions that should be included in CTV are still controversial. In this article, clinical data of cervical surgery were retrospectively analyzed, clinical trials associated with lymph node metastases of supraglottic laryngeal carcinoma were reviewed, the distribution characteristics and risk factors of positive lymph nodes were summarized, aiming to provide reference for the precise delineation of prophylactic CTV in radical radiotherapy for supraglottic laryngeal carcinoma.