Evaluation of the efficacy and safety of vertebroplasty as a day surgery procedure / 中华老年医学杂志

ABSTRACT

Objective:To investigate the surgical efficacy and safety of vertebroplasty as a day surgery procedure for osteoporotic vertebral fracture(OVF).Methods:A total of 159 patients with OVF undergoing vertebroplasty in Department of Orthopaedics, Beijing Hospital were enrolled and the clinical data were analyzed in this retrospective cohort study.They were grouped as the day-surgery group(n=81, the hospitalization, operation, briefly observation, recovered and discharged after treatment were completed during 1 working day)and as the hospitalized surgery group(n=78, patients stayed overnight in hospital or were hospitalized more than 24 hours). The mean follow-up time was 12.3 months(12-14 months). Pain score, analgesic drug use and activity ability were compared between the two groups before operation, 1 week after operation and at the last follow-up.Clinical effect, intra-operative and post-operative complications in the two groups were observed.Results:In intra-group comparison in the day-surgery group, the pain score, analgesic drug use and activity ability showed statistically significant differences at 1 week after surgery and at last follow-up as compared with those before treatment( P<0.01). No significant differences in pain score, analgesic drug use and activity ability were found between the day-surgery group and the hospitalized surgery group at 1 week after operation and at the last follow-up(2.3±1.2 vs.2.4±1.2, 1.7±0.9 vs.1.6±0.8; 1.5±0.3 vs.1.3±0.7, 1.8±0.4 vs.1.6±0.6; 1.3±0.7 vs.1.3±0.9, 1.3±0.6 vs.1.4±0.5; all P>0.05). The blood loss during surgery, postoperative complications including cerebrospinal fluid leakage, bone cement leakage, hematoma or infection at the puncture site, nerve root stimulation symptoms and re-fracture had no statistical difference between the two group(all P>0.05). Conclusions:The vertebroplasty as a day-surgery mode for osteoporotic vertebral fracture can improve the postoperative VAS score and activity ability, and decrease pain medication use.Efficacy and safety of a day-surgery for OVF are comparable to those of the hospitalized operation.