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A correlational research between sleep duration, timing and the risk of osteoporosis in postmenopausal women / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism ; (12): 949-955, 2020.
Artigo em Chinês | WPRIM | ID: wpr-870119
ABSTRACT

Objective:

To investigate the correlation between sleep duration, sleep timing and the risk of osteoporosis in postmenopausal women, to identify contributing mechanisms and guide the prevention and treatment of osteoporosis.

Methods:

A total of 5 449 postmenopausal women were included in this study. All participants completed questionnaires, medical examinations, blood test and the measurement of bone mineral density using calcaneal quantitative ultrasonography. After adjusting for potential confounders, logistic regression model was used to assess the association of sleep duration, sleep timing with the risk of osteoporosis.

Results:

In postmenopausal women, there were significant differences in sleep duration and timing among groups with different risk of osteoporosis( P<0.05). After controlling ages, BMI, diabetes, hypertension, dyslipidemia, smoking, alcohol consumption and physical activity, sleep duration was correlated with the risk of osteoporosis, long sleep duration(≥9 h)increased the risk of osteoporosis( OR=1.39, 95% CI 1.17-1.65, P<0.05)compared with the group with sleep duration of 7~8 hours. In analysis of the combined effect of sleep duration and sleep time on the risk of osteoporosis, compared with normal sleep duration(7-8 h)and normal sleep timing(22 00-23 00), long sleep duration(≥9 h)and normal sleep timing(22 00-23 00)increased the risk of osteoporosis( OR=1.38, 95% CI 1.01-1.87, P<0.05), which was higher in the group of long sleep duration(≥9 h)and late sleep timing(≥23 00; OR=1.43, 95% CI 1.01-2.01, P<0.05).

Conclusion:

Long sleep duration(≥9 h)and late sleep timing(≥22 00)are risk factors for the increased risk of osteoporosis in postmenopausal women, the late sleep timing leads to the higher risk.
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de etiologia / Estudo prognóstico / Pesquisa qualitativa / Fatores de risco Idioma: Chinês Revista: Chinese Journal of Endocrinology and Metabolism Ano de publicação: 2020 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de etiologia / Estudo prognóstico / Pesquisa qualitativa / Fatores de risco Idioma: Chinês Revista: Chinese Journal of Endocrinology and Metabolism Ano de publicação: 2020 Tipo de documento: Artigo