Analysis of factors associated with skin lesion distribution in 1 125 patients with non-segmental vitiligo / 中华皮肤科杂志
Chinese Journal of Dermatology
;
(12): 214-219, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-870251
ABSTRACT
Objective To analyze correlations of the distribution of non-segmental vitiligo lesions with gender,age of onset,duration of disease,personal and family history of autoimmune diseases,family history of vitiligo,and so on.Methods Clinical data were collected from 1 125 patients with confirmed nonsegmental vitiligo in Department of Dermatology,Beijing Hospital from January 2009 to January 2019,and analyzed retrospectively.Statistical analysis was carried out with SPSS 20.0 software by using independentsample t test and chi-square test.Results Of the 1 125 patients with non-segmental vitiligo,599 were males and 526 were females,with a male-to-female ratio of 1.141.Their age of onset was 27.9 ± 17.1 years,and duration of disease was 5.2 ± 8.0 years.Skin lesions mostly occurred on the trunk (544 cases,48.4%) and face (535 cases,47.6%),followed by acral regions (430 cases,38.2%),extremities (297 cases,26.4%) and neck (231 cases,20.5%).The perioral region (17.2%),hands (47.9%) and genital region (14.5%) in the 599 male patients were more frequently affected than those in the 526 females (9.7%,22.6%,6.3%,x2 =13.33,77.66,20.01,respectively,all P < 0.001),while the neck (27.0%) was more frequently affected in the female patients than in the male patients (14.9%,x2 =25.29,P < 0.001).The age of onset was significantly lower in the patients with vitiligo lesions involving the legs,knees,feet,trunk,genital and periocular regions than in those without skin lesions on the above corresponding body sites (all P < 0.05),but significantly higher in the patients with vitiligo lesions involving the arms and hands than in those without lesions on the above 2 sites (both P < 0.05).Vitiligo lesions more likely occurred on the hands of patients with a personal or family history of autoimmune thyroid diseases compared with those without the personal or family history (50.0% vs.27.9%,x2 =6.62,P =0.010).The trunk was more frequently affected in the patients with a family history of vitiligo than in those without (59.6% vs.45.7%,x2 =13.36,P < 0.001).Conclusion The distribution of non-segmental vitiligo lesions are correlated to some extent with gender,age of onset,personal and family history of autoimmune diseases and family history of vitiligo.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Dermatology
Ano de publicação:
2020
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS