Progress in autophagy-regulated immune cell differentiation / 中华微生物学和免疫学杂志

ABSTRACT

As a conservative lysosomal degradation pathway, autophagy possess various functions that have been well studied in the immune system. Regulatory effects of autophagy on the differentiation of immune cells have been gradually revealed. In order to investigate the specific mechanisms, it is very necessary to summarize the role of autophagy in the proliferation, development and differentiation of immune cells. Effects of autophagy on the functions and differentiation of immune cells have been summarized by introducing the selective degradation function of autophagy in some articles. This review focused on some classical immune cells and elucidated the important regulatory effects of autophagy and the nutrient signaling metabolic pathways involved in autophagy on immune cell differentiation.