Oral Testosterone Undecanoate Versus Transdermal Testosterone Gel for the Treatment of Testosterone Deficiency Syndrome: A Retrospective Comparative Study / 대한남성과학회지
Korean Journal of Andrology
;
: 197-202, 2010.
Artigo
em Coreano
| WPRIM
| ID: wpr-87190
ABSTRACT
PURPOSE:
Oral testosterone undecanoate and transdermal testosterone gel are the testosterone formulas widely prescribed as hormonal replacement for tesosterone deficiency syndrome (TDS) in male patients. We evaluated the changes in serum testosterone level and the effects of these medicines. MATERIALS ANDMETHODS:
The medical records of 162 patients who were diagnosed with TDS based on serum testosterone (0.05). The initial and final testosterone levels of the two groups were not significantly different. However, the peak level during treatment was significantly higher in group II (p<0.05). The maximal increment of testosterone level was also significantly higher in group II. Initially, group II reached its peak testosterone level earlier than group I. The final serum levels were not significantly different after adjustment of dosages in group I. Testosterone replacement significantly decreased the AMS scales in both groups.CONCLUSIONS:
Both oral testosterone undecanoate and transdermal testosterone gel improved the serum testosterone level and symptom score for those with TDS. Transdermal testosterone gel may reach the peak serum testosterone level faster than oral testosterone undecanoate. Large prospective studies are required to assess the precise role of testosterone replacement therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sorbitol
/
Comprimidos
/
Testosterona
/
Pesos e Medidas
/
Envelhecimento
/
Tiramina
/
Prontuários Médicos
/
Estudos Retrospectivos
/
Seguimentos
/
Hipogonadismo
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Andrology
Ano de publicação:
2010
Tipo de documento:
Artigo
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