Effects of Loquat Lung-Cleaning Decoction on acne vulgaris with fusidic acid cream / 中华医学美学美容杂志

ABSTRACT

Objective:To investigate the clinical effect of Loquat Lung-Cleaning Decoction combined with fusidic acid cream in the treatment of acne vulgaris.Methods:From March 2019 to November 2019, 50 patients (9 males and 21 females, aged 13-31 years) with acne vulgaris were collected from the acne clinic of the dermatology department of the Hospital and divided into the experimental group and the control group with 25 cases in each group. The control group was treated with fusidic acid cream alone, and the experimental group was treated with Loquat Lung-Cleaning Decoction combined with fusidic acid cream. Six weeks after treatment, the clinical effect and adverse reactions were observed.Results:In the experimental group, 7 cases were cured, 10 cases were markedly effective, 6 cases were effective, but 2 cases were ineffective; the apparent efficiency was 68%. In the control group, 4 cases were cured, 6 cases were markedly effective, 9 cases were effective, and 6 cases were ineffective; the apparent efficiency was 40%. The effective rate of treatment in the experimental group was significantly higher than that in the control group, and the area of skin lesions was significantly smaller than that in the control group. The difference was statistically significant (rank sum test Z=1.98442, P=0.0472<0.05, rate analysis χ2 test χ2=3.945, P<0.05). Conclusions:The treatment of acne vulgaris with Loquat Lung-Cleaning Decoction and fusidic acid cream is effective.